BDBM50294706 4-((2-chlorobenzyl)(3-methyl-1-(1-methyl-1H-tetrazol-5-yl)butyl)amino)-2-chlorobenzonitrile::CHEMBL561713

SMILES CC(C)CC(N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1)c1nnnn1C

InChI Key InChIKey=DAZGBWZWTXJDJO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294706   

TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294706(4-((2-chlorobenzyl)(3-methyl-1-(1-methyl-1H-tetraz...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at progesterone receptor in human T47D cells by alkaline phosphatase release based reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294706(4-((2-chlorobenzyl)(3-methyl-1-(1-methyl-1H-tetraz...)
Affinity DataIC50: 5nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294706(4-((2-chlorobenzyl)(3-methyl-1-(1-methyl-1H-tetraz...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed