BDBM50294745 3-Benzyl-4-[3-(benzyloxy)phenyl]-8-chlorocinnoline::CHEMBL552157

SMILES Clc1cccc2c(c(Cc3ccccc3)nnc12)-c1cccc(OCc2ccccc2)c1

InChI Key InChIKey=WLJAORRKUJBIBV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294745   

TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294745(3-Benzyl-4-[3-(benzyloxy)phenyl]-8-chlorocinnoline...)
Affinity DataIC50: 4.60E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294745(3-Benzyl-4-[3-(benzyloxy)phenyl]-8-chlorocinnoline...)
Affinity DataIC50: 1.80E+5nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed