BDBM50294751 CHEMBL551584::[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][5-fluoro-2-(trifluoromethyl)benzyl]amine

SMILES Fc1ccc(c(CNc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)c1)C(F)(F)F

InChI Key InChIKey=ITLFECPZLKVOJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294751   

TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294751([3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][5-fluor...)
Affinity DataIC50: 6.20E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294751([3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][5-fluor...)
Affinity DataIC50: 1.00E+6nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed