BDBM50294755 3-Benzyl-4-(3-{[2-fluoro-3-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline::CHEMBL550441

SMILES Fc1c(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(cccc23)C(F)(F)F)cccc1C(F)(F)F

InChI Key InChIKey=CGTFWGIWVIWUQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294755   

TargetOxysterols receptor LXR-beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294755(3-Benzyl-4-(3-{[2-fluoro-3-(trifluoromethyl)benzyl...)
Affinity DataIC50: 6.30E+4nMAssay Description:Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294755(3-Benzyl-4-(3-{[2-fluoro-3-(trifluoromethyl)benzyl...)
Affinity DataIC50: 1.34E+6nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells co-transfected with Gal4-DBD by luciferase transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed