BDBM50294785 3,3-Dimethyl-pentanedioic acid cyclopropylamide(5-hydroxy-adamantan-2-yl)-amide::CHEMBL552519

SMILES CC(C)(CC(=O)NC1CC1)CC(=O)N[C@H]1C2CC3CC1C[C@@](O)(C3)C2

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294785   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50294785(3,3-Dimethyl-pentanedioic acid cyclopropylamide(5-...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as cortisol level after 150 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed