BDBM50295753 1-(benzo[c][1,2,5]oxadiazol-4-ylsulfonyl)-1H-pyrrolo[3,2-b]pyridin-6-amine::CHEMBL562063

SMILES Nc1cnc2ccn(c2c1)S(=O)(=O)c1cccc2nonc12

InChI Key InChIKey=CLCQRCXCSJSVKF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50295753   

TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295753(1-(benzo[c][1,2,5]oxadiazol-4-ylsulfonyl)-1H-pyrro...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant His-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295753(1-(benzo[c][1,2,5]oxadiazol-4-ylsulfonyl)-1H-pyrro...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295753(1-(benzo[c][1,2,5]oxadiazol-4-ylsulfonyl)-1H-pyrro...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295753(1-(benzo[c][1,2,5]oxadiazol-4-ylsulfonyl)-1H-pyrro...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of c-Met phosphorylation in human A549 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed