BDBM50296014 2-methyl-2-(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)propanoic acid::CHEMBL541759

SMILES CC(C)(C(O)=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1ccccc1

InChI Key InChIKey=FHYOMNYZIGSVNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296014   

TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296014(2-methyl-2-(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3...)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296014(2-methyl-2-(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3...)
Affinity DataIC50:  50nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed