BDBM50296045 CHEMBL562847::N-(1-(6-oxo-1,6-dihydropyridin-3-yl)pentyl)-2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide

SMILES CCCCC(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1ccc(=O)[nH]c1

InChI Key InChIKey=ORCCEUNUHQADKD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296045   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50296045(N-(1-(6-oxo-1,6-dihydropyridin-3-yl)pentyl)-2-(1-(...)
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50296045(N-(1-(6-oxo-1,6-dihydropyridin-3-yl)pentyl)-2-(1-(...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50296045(N-(1-(6-oxo-1,6-dihydropyridin-3-yl)pentyl)-2-(1-(...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed