BDBM50296300 CHEMBL550785::N-(5-(hydroxy(3-(trifluoromethyl)phenyl)methyl)thiazol-2-yl)-3-(2-hydroxyethoxy)-4-methoxybenzamide

SMILES COc1ccc(cc1OCCO)C(=O)Nc1ncc(s1)C(O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=HDBOHAFZZFIARA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296300   

TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296300(N-(5-(hydroxy(3-(trifluoromethyl)phenyl)methyl)thi...)
Affinity DataIC50: 276nMAssay Description:Inhibition of stearoyl-CoA desaturase 1 in mouse microsome assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296300(N-(5-(hydroxy(3-(trifluoromethyl)phenyl)methyl)thi...)
Affinity DataIC50: 884nMAssay Description:Inhibition of stearoyl-CoA desaturase 1 in human microsome assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed