BDBM50296675 (E)-1-Adamantan-1-yl-3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-propenone::CHEMBL556707

SMILES O=C(\C=C\c1cnc2OCCOc2c1)C12CC3CC(CC(C3)C1)C2

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296675   

TargetMetabotropic glutamate receptor 1(Rat)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296675((E)-1-Adamantan-1-yl-3-(2,3-dihydro-benzo[1,4]diox...)
Affinity DataKi:  641nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296675((E)-1-Adamantan-1-yl-3-(2,3-dihydro-benzo[1,4]diox...)
Affinity DataKi:  6.23E+3nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed