BDBM50296682 8-hexyl-7-methoxy-2,3-dihydrocyclopenta[c]chromen-4(1H)-one::CHEMBL557769

SMILES CCCCCCc1cc2c3CCCc3c(=O)oc2cc1OC

InChI Key InChIKey=CUQRMRTXIDBXOS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296682   

TargetMetabotropic glutamate receptor 1(Rat)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296682(8-hexyl-7-methoxy-2,3-dihydrocyclopenta[c]chromen-...)
Affinity DataIC50: 2.39E+4nMAssay Description:Allosteric antagonist activity at mGluR1 in Sprague-Dawley rat cerebellar granule cells assessed as accumulation of [3H]inositol phosphate by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296682(8-hexyl-7-methoxy-2,3-dihydrocyclopenta[c]chromen-...)
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed