BDBM50296683 4-(5-pentylpyridin-2-yl)phenyl 4-ethylcyclohexanecarboxylate::CHEMBL564000

SMILES CCCCCc1ccc(nc1)-c1ccc(OC(=O)C2CCC(CC)CC2)cc1

InChI Key InChIKey=GTVRLXJURIMUBV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296683   

TargetMetabotropic glutamate receptor 1(Rat)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296683(4-(5-pentylpyridin-2-yl)phenyl 4-ethylcyclohexanec...)
Affinity DataIC50: 2.25E+4nMAssay Description:Allosteric antagonist activity at mGluR1 in Sprague-Dawley rat cerebellar granule cells assessed as accumulation of [3H]inositol phosphate by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296683(4-(5-pentylpyridin-2-yl)phenyl 4-ethylcyclohexanec...)
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed