BDBM50296754 CHEMBL558647::N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)pyrrolidin-2-yl)methyl)-N-cyclopropyl-1,1,1-trifluoromethanesulfonamide

SMILES N[C@@H](CC(=O)N1CCC[C@H]1CN(C1CC1)S(=O)(=O)C(F)(F)F)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=LOTNXXFJKBJHID-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50296754   

TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296754(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296754(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296754(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296754(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of DPP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296754(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human recombinant DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed