BDBM50296757 CHEMBL564283::N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)pyrrolidin-2-yl)methyl)-1,1,1-trifluoromethanesulfonamide

SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNS(=O)(=O)C(F)(F)F)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=GGUFZJIZPROIJW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50296757   

TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296757(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 12nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296757(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296757(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of DPP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296757(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human recombinant DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296757(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed