BDBM50296765 CHEMBL558322::N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)pyrrolidin-2-yl)methyl)pivalamide

SMILES CC(C)(C)C(=O)NC[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=PPIXLDHQYDDLOH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50296765   

TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296765(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296765(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of DPP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296765(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296765(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50296765(N-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human recombinant DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed