BDBM50296868 (1S,13R)-22-(cyclopropylmethyl)-10,22-diazahexacyclo[11.7.4.0^{1,13}.0^{3,11}.0^{4,9}.0^{14,19}]tetracosa-3(11),4(9),5,7,14(19),15,17-heptaen-16-ol::CHEMBL562340

SMILES Oc1ccc2C[C@@]34CN(CC5CC5)CC[C@@]3(Cc3[nH]c5ccccc5c3C4)c2c1

InChI Key InChIKey=KSZYKGRYELDMJF-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50296868   

TargetDelta-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50296868((1S,13R)-22-(cyclopropylmethyl)-10,22-diazahexacyc...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50296868((1S,13R)-22-(cyclopropylmethyl)-10,22-diazahexacyc...)
Affinity DataEC50:  33nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50296868((1S,13R)-22-(cyclopropylmethyl)-10,22-diazahexacyc...)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50296868((1S,13R)-22-(cyclopropylmethyl)-10,22-diazahexacyc...)
Affinity DataKi:  523nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50296868((1S,13R)-22-(cyclopropylmethyl)-10,22-diazahexacyc...)
Affinity DataKi:  704nMAssay Description:Displacement of [3H]U50488 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50296868((1S,13R)-22-(cyclopropylmethyl)-10,22-diazahexacyc...)
Affinity DataKi:  2.55E+3nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed