BDBM50296913 CHEMBL561396::N-((2-(3-chloropyridin-2-yl)-5-isopropyl-1-(6-methylpyridin-3-yl)-1H-imidazol-4-yl)methyl)cyclopentanamine

SMILES CC(C)c1c(CNC2CCCC2)nc(-c2ncccc2Cl)n1-c1ccc(C)nc1

InChI Key InChIKey=BOWSGWFJDZSKQS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296913   

TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296913(N-((2-(3-chloropyridin-2-yl)-5-isopropyl-1-(6-meth...)
Affinity DataIC50: 4.70nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296913(N-((2-(3-chloropyridin-2-yl)-5-isopropyl-1-(6-meth...)
Affinity DataIC50: 9.60nMAssay Description:Antagonist activity at human cloned ORL1 receptor expressed in CHO cells assessed as inhibition of nociceptin/orphanin FQ-stimulated [35S]GTPgammaS b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296913(N-((2-(3-chloropyridin-2-yl)-5-isopropyl-1-(6-meth...)
Affinity DataIC50: 9.90E+3nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cells overexpressing Ikr channel proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed