BDBM50297065 CHEMBL563096::N-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-(5-methoxypyridin-2-yl)benzamide

SMILES COc1ccc(nc1)-c1ccc(cc1)C(=O)Nc1ccc2nc(C3CC3)c(C)n2c1

InChI Key InChIKey=BKHHAWLKYJADJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297065   

TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297065(N-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-y...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297065(N-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-y...)
Affinity DataIC50: 122nMAssay Description:Antagonist activity at human MCH1 receptor expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed