BDBM50297618 1-(3-Hydroxy-adamantan-1-yl)-3-{1-[1-(4-trifluoromethyl-phenyl)-1H-pyrrol-3-ylmethyl]-piperidin-4-yl}-urea::CHEMBL552144

SMILES OC12CC3CC(C1)CC(C3)(C2)NC(=O)NC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297618   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297618(1-(3-Hydroxy-adamantan-1-yl)-3-{1-[1-(4-trifluorom...)
Affinity DataIC50: 82nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297618(1-(3-Hydroxy-adamantan-1-yl)-3-{1-[1-(4-trifluorom...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed