BDBM50297622 1-(1-(1H-imidazol-1-yl)propan-2-yl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea::CHEMBL549930

SMILES CC(Cn1ccnc1)NC(=O)NC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1

InChI Key InChIKey=JHYBPHVVKVPUAR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297622   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297622(1-(1-(1H-imidazol-1-yl)propan-2-yl)-3-(1-((1-(4-(t...)
Affinity DataIC50: 308nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297622(1-(1-(1H-imidazol-1-yl)propan-2-yl)-3-(1-((1-(4-(t...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant CYP3A4 after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297622(1-(1-(1H-imidazol-1-yl)propan-2-yl)-3-(1-((1-(4-(t...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed