BDBM50297634 (S)-1-(2-hydroxy-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea::CHEMBL557329

SMILES OC[C@@H](NC(=O)NC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1ccccc1

InChI Key InChIKey=SABBBCPABFDZNM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297634   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297634((S)-1-(2-hydroxy-1-phenylethyl)-3-(1-((1-(4-(trifl...)
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297634((S)-1-(2-hydroxy-1-phenylethyl)-3-(1-((1-(4-(trifl...)
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of human recombinant CYP3A4 after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297634((S)-1-(2-hydroxy-1-phenylethyl)-3-(1-((1-(4-(trifl...)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed