BDBM50297659 CHEMBL540166::N-cyclohexyl-4-methyl-6-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine

SMILES Cc1cc(nc(NC2CCCCC2)n1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=NTVJZYVURSEDAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297659   

TargetProstaglandin G/H synthase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297659(N-cyclohexyl-4-methyl-6-(4-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of human COX2 expressed in baculovirus-infected SF9 cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297659(N-cyclohexyl-4-methyl-6-(4-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX1 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 treated 1 hr before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed