BDBM50297682 2-(cyclohexylmethoxy)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidine::CHEMBL564729

SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(nc(OCC2CCCCC2)n1)C(F)(F)F

InChI Key InChIKey=CXMNVVPEMHYESO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297682   

TargetProstaglandin G/H synthase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297682(2-(cyclohexylmethoxy)-4-(4-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human COX2 expressed in baculovirus-infected SF9 cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297682(2-(cyclohexylmethoxy)-4-(4-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX1 expressed in baculovirus-infected SF9 cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed