BDBM50297704 4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-phenethylpyrimidine::CHEMBL552145

SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(CCc2ccccc2)nc1-c1ccc(F)cc1

InChI Key InChIKey=RGXSMAYXKHOHSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297704   

TargetProstaglandin G/H synthase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297704(4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-...)
Affinity DataIC50: 5.26E+3nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297704(4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-...)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of human COX1 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed