BDBM50297708 (4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidin-2-yl)(phenyl)methanol::CHEMBL557128

SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(nc1-c1ccc(F)cc1)C(O)c1ccccc1

InChI Key InChIKey=GEQJBYFLKSKJBG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297708   

TargetProstaglandin G/H synthase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50297708((4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)py...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed