BDBM50297894 2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL204171

SMILES O=S(=O)(c1ccccc1)C1(CCCN2CCc3ccccc3C2)CCC1

InChI Key InChIKey=DHXAAEUVXXASMB-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50297894   

Target5-hydroxytryptamine receptor 7(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297894(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297894(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)
Affinity DataKi:  8nMAssay Description:Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50297894(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)
Affinity DataKi:  35nMAssay Description:Binding affinity to 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297894(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297894(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50297894(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)
Affinity DataKi:  65nMAssay Description:Binding affinity to 5HT2A receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed