BDBM50297926 2-Hydroxy-2-phenethyl-pentanedioic acid 5-[((S)-1-benzylcarbamoyl-2-methyl-propyl)-amide]1-{[3-[(R)-1-(4-fluoro-phenyl)-ethylcarbamoyl]-5-(methanesulfonyl-methyl-amino)-phenyl]-amide}::CHEMBL539396

SMILES CC(C)[C@H](NC(=O)CCC(O)(CCc1ccccc1)C(=O)Nc1cc(cc(c1)C(=O)N[C@H](C)c1ccc(F)cc1)N(C)S(C)(=O)=O)C(=O)NCc1ccccc1

InChI Key InChIKey=QPJTWJJNHNQFTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297926   

TargetBeta-secretase 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297926(2-Hydroxy-2-phenethyl-pentanedioic acid 5-[((S)-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed