BDBM50297938 2-Benzyl-2-hydroxy-pentanedioic acid 1-{[3-[(R)-1-(4-fluoro-phenyl)-ethylcarbamoyl]-5-(methanesulfonyl-methyl-amino)-phenyl]-amide}5-[((1S,2R)-2-hydroxy-indan-1-yl)-amide]::CHEMBL558760

SMILES C[C@@H](NC(=O)c1cc(NC(=O)C(O)(CCC(=O)N[C@@H]2[C@H](O)Cc3ccccc23)Cc2ccccc2)cc(c1)N(C)S(C)(=O)=O)c1ccc(F)cc1

InChI Key InChIKey=HXYWBBUDWDMDQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297938   

TargetBeta-secretase 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297938(2-Benzyl-2-hydroxy-pentanedioic acid 1-{[3-[(R)-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed