BDBM50297974 (R)-3-(1-(2-chloro-4-((2-hydroxyethylamino)methyl)phenyl)ethoxy)-5-(imidazo[1,2-a]pyridin-3-yl)thiophene-2-carboxamide::CHEMBL563363

SMILES C[C@@H](Oc1cc(sc1C(N)=O)-c1cnc2ccccn12)c1ccc(CNCCO)cc1Cl

InChI Key InChIKey=PPPSOHXHWPYJTF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297974   

TargetSerine/threonine-protein kinase PLK1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297974((R)-3-(1-(2-chloro-4-((2-hydroxyethylamino)methyl)...)
Affinity DataIC50: 21nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297974((R)-3-(1-(2-chloro-4-((2-hydroxyethylamino)methyl)...)
Affinity DataEC50:  1.84E+5nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed