BDBM50297981 (R)-3-(1-(2-chloro-4-((3-oxopiperazin-1-yl)methyl)phenyl)ethoxy)-5-(imidazo[1,2-a]pyridin-3-yl)thiophene-2-carboxamide::CHEMBL550475

SMILES C[C@@H](Oc1cc(sc1C(N)=O)-c1cnc2ccccn12)c1ccc(CN2CCNC(=O)C2)cc1Cl

InChI Key InChIKey=KDBHWYQEQOHRMN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297981   

TargetSerine/threonine-protein kinase PLK1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297981((R)-3-(1-(2-chloro-4-((3-oxopiperazin-1-yl)methyl)...)
Affinity DataIC50: 12nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297981((R)-3-(1-(2-chloro-4-((3-oxopiperazin-1-yl)methyl)...)
Affinity DataEC50:  1.70E+6nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed