BDBM50297995 (+/-)-5-(2-fluorophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid::CHEMBL562632

SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1ccccc1F

InChI Key InChIKey=IBIKXOKLTWYROG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297995   

TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297995((+/-)-5-(2-fluorophenyl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataIC50: 270nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297995((+/-)-5-(2-fluorophenyl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataEC50:  4.40E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed