BDBM50298020 2,2,2-trifluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)ethyl)acetamide::CHEMBL549389

SMILES Oc1ccc(cc1F)C1=NOC(CCNC(=O)C(F)(F)F)C1

InChI Key InChIKey=UCWRVTGTONITDZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298020   

TargetMacrophage migration inhibitory factor(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298020(2,2,2-trifluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298020(2,2,2-trifluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298020(2,2,2-trifluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed