BDBM50298110 2-(4,4,5,5,5-Pentafluoro-3-mercapto-pentanoylamino)-3-phenyl-propionic acid::CHEMBL558146

SMILES OC(=O)C(Cc1ccccc1)NC(=O)CC(S)C(F)(F)C(F)(F)F

InChI Key InChIKey=DYMMAGGCPNJADM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298110   

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298110(2-(4,4,5,5,5-Pentafluoro-3-mercapto-pentanoylamino...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298110(2-(4,4,5,5,5-Pentafluoro-3-mercapto-pentanoylamino...)
Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298110(2-(4,4,5,5,5-Pentafluoro-3-mercapto-pentanoylamino...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed