BDBM50298511 2-(4-chlorophenoxy)-N-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)acetamide::CHEMBL576153

SMILES Clc1ccc(OCC(=O)Nc2nc3nn(CCCc4ccccc4)cc3c3nc(nn23)-c2ccco2)cc1

InChI Key InChIKey=GJKDVRRUKCQKHE-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50298511   

TargetAdenosine receptor A2a(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298511(2-(4-chlorophenoxy)-N-(2-(furan-2-yl)-8-(3-phenylp...)
Affinity DataKi:  27.2nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298511(2-(4-chlorophenoxy)-N-(2-(furan-2-yl)-8-(3-phenylp...)
Affinity DataKi:  71.1nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298511(2-(4-chlorophenoxy)-N-(2-(furan-2-yl)-8-(3-phenylp...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298511(2-(4-chlorophenoxy)-N-(2-(furan-2-yl)-8-(3-phenylp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed