BDBM50298540 5-[(3-Thienylmethyl)carbonyl]amino-8-(2-phenyl ethyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine::CHEMBL572419

SMILES O=C(Cc1ccsc1)Nc1nc2nn(CCc3ccccc3)cc2c2nc(nn12)-c1ccco1

InChI Key InChIKey=LRHLBUAJTSIOMS-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50298540   

TargetAdenosine receptor A2a(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298540(5-[(3-Thienylmethyl)carbonyl]amino-8-(2-phenyl eth...)
Affinity DataKi:  12.9nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298540(5-[(3-Thienylmethyl)carbonyl]amino-8-(2-phenyl eth...)
Affinity DataKi:  22.8nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298540(5-[(3-Thienylmethyl)carbonyl]amino-8-(2-phenyl eth...)
Affinity DataKi:  726nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298540(5-[(3-Thienylmethyl)carbonyl]amino-8-(2-phenyl eth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed