BDBM50298549 2-(3-chlorophenyl)-N-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)acetamide::CHEMBL583960

SMILES Cn1cc2c(n1)nc(NC(=O)Cc1cccc(Cl)c1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=CAEIDEVSQAUGPM-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50298549   

TargetAdenosine receptor A3(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298549(2-(3-chlorophenyl)-N-(2-(furan-2-yl)-8-methyl-8H-p...)
Affinity DataKi:  1.94nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298549(2-(3-chlorophenyl)-N-(2-(furan-2-yl)-8-methyl-8H-p...)
Affinity DataKi:  30.5nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298549(2-(3-chlorophenyl)-N-(2-(furan-2-yl)-8-methyl-8H-p...)
Affinity DataKi:  410nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50298549(2-(3-chlorophenyl)-N-(2-(furan-2-yl)-8-methyl-8H-p...)
Affinity DataIC50: 8.96E+3nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed