BDBM50298709 CHEMBL585553::Stylissadine A

SMILES NC1=[NH+]C2(O)C(N1)OC1NC(=[NH2+])NC11C(OC3C(CNC(=O)c4cc(Br)c(Br)[nH]4)C(CNC(=O)c4cc(Br)c(Br)[nH]4)C4C5(O)NC(=[NH2+])NC5OC5NC(=[NH2+])NC345)C(CNC(=O)c3cc(Br)c(Br)[nH]3)C(CNC(=O)c3cc(Br)c(Br)[nH]3)C21

InChI Key InChIKey=YJHWJTAJYZABEV-UHFFFAOYSA-R

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50298709   

TargetP2X purinoceptor 7(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298709(Stylissadine A | CHEMBL585553)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced pore formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed