BDBM50299749 (2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]-2-hydroxymethyl-piperidine-3,4,5-triol::CHEMBL574645::N-adamantanemethyloxypentyl-1-deoxynojirimycin
SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC12CC3CC(CC(C3)C1)C2
InChI Key InChIKey=XVYLNHVEAOOEGI-FAIWKWDXSA-N
Data 30 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 30 hits for monomerid = 50299749
Affinity DataIC50: 500nMAssay Description:Inhibition of sucrase by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of non-lysosomal glucosylceramidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of GBA1 (unknown origin) using beta-D-[1-14C]glucocerebroside assessed as 4-methylumbelliferrone by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of intestinal sucrase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of intestinal lactase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of intestinal maltase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human GBA2More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of GCS by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of lactase by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glycogen glycogen de-branching enzyme by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of maltase by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of lactase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of sucrase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant GBA2 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant GBA1 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of GCS in human A549 cells assessed as decrease in GM1 synthesis after 72 hrs by Fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of non-lysosomal glucosylceramidase in cultured melanoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human lysosomal alpha glucosidaseMore data for this Ligand-Target Pair