BDBM50299763 CHEMBL574225::N-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluorophenyl)-3-(3-fluorophenyl)-2-oxoimidazolidine-1-carboxamide

SMILES COc1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4cccc(F)c4)cc3F)c2cc1OC

InChI Key InChIKey=RPWBDLXYCZXFDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299763   

TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50299763(N-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluoropheny...)
Affinity DataIC50: 50nMAssay Description:Inhibition of GST-tagged c-Met expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50299763(N-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluoropheny...)
Affinity DataIC50: 200nMAssay Description:Inhibition of TPR-Met assessed as autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed