BDBM50299766 CHEMBL572389::N-(3-fluoro-4-(6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinolin-4-yloxy)phenyl)-2-oxo-3-phenylimidazolidine-1-carboxamide

SMILES COc1cc2c(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)ccnc2cc1OCC1CCN(C)CC1

InChI Key InChIKey=HZAXAFBDACOIJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299766   

TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50299766(N-(3-fluoro-4-(6-methoxy-7-((1-methylpiperidin-4-y...)
Affinity DataIC50: 50nMAssay Description:Inhibition of GST-tagged c-Met expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50299766(N-(3-fluoro-4-(6-methoxy-7-((1-methylpiperidin-4-y...)
Affinity DataIC50: 130nMAssay Description:Inhibition of TPR-Met assessed as autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed