BDBM50299771 CHEMBL574093::N-(4-(6,7-bis(2-methoxyethoxy)quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamide

SMILES COCCOc1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2cc1OCCOC

InChI Key InChIKey=VCHWZJKWEQBXSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299771   

TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50299771(N-(4-(6,7-bis(2-methoxyethoxy)quinolin-4-yloxy)-3-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of TPR-Met assessed as autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50299771(N-(4-(6,7-bis(2-methoxyethoxy)quinolin-4-yloxy)-3-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of GST-tagged c-Met expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed