BDBM50299781 1-(2-((2-cyclopropylphenoxy)methyl)phenyl)piperazine::CHEMBL575289

SMILES C(Oc1ccccc1C1CC1)c1ccccc1N1CCNCC1

InChI Key InChIKey=OIRUCIGVEPJTON-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50299781   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299781(1-(2-((2-cyclopropylphenoxy)methyl)phenyl)piperazi...)
Affinity DataKi:  53nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50299781(1-(2-((2-cyclopropylphenoxy)methyl)phenyl)piperazi...)
Affinity DataKi:  192nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299781(1-(2-((2-cyclopropylphenoxy)methyl)phenyl)piperazi...)
Affinity DataKi:  466nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299781(1-(2-((2-cyclopropylphenoxy)methyl)phenyl)piperazi...)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed