BDBM50300096 (S)-ethyl 4-(6-(4-(3-(2-fluoroethyl)ureido)phenyl)-4-(3-methylmorpholino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate::CHEMBL576782

SMILES CCOC(=O)N1CCC(CC1)n1ncc2c(nc(nc12)-c1ccc(NC(=O)NCCF)cc1)N1CCOC[C@@H]1C

InChI Key InChIKey=LOSCOCADDAFDQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300096   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300096((S)-ethyl 4-(6-(4-(3-(2-fluoroethyl)ureido)phenyl)...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FLAG-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50300096((S)-ethyl 4-(6-(4-(3-(2-fluoroethyl)ureido)phenyl)...)
Affinity DataIC50: 521nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed