BDBM50300103 CHEMBL575745::trans-1-cyclopentyl-6-(4-methyl-1-(3-methylbenzyl)pyrrolidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

SMILES Cc1cccc(CN2C[C@@H](C)[C@H](c3nc4c(cnn4C4CCCC4)c(=O)[nH]3)C2)c1

InChI Key InChIKey=GYKSGQMBFSLYGY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50300103   

LigandChemical structure of BindingDB Monomer ID 50300103BDBM50300103(trans-1-cyclopentyl-6-(4-methyl-1-(3-methylbenzyl)...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50300103BDBM50300103(trans-1-cyclopentyl-6-(4-methyl-1-(3-methylbenzyl)...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50300103BDBM50300103(trans-1-cyclopentyl-6-(4-methyl-1-(3-methylbenzyl)...)
Affinity DataIC50: 563nMAssay Description:Inhibition of human recombinant PDE1C expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50300103BDBM50300103(trans-1-cyclopentyl-6-(4-methyl-1-(3-methylbenzyl)...)
Affinity DataIC50: 563nMAssay Description:Inhibition of human recombinant PDE1C expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed