BDBM50300200 6alpha-ethyl-23(R)-methyl-cholic acid::CHEMBL565278

SMILES CC[C@H]1[C@@H](O)[C@H]2[C@@H]3CC[C@H]([C@H](C)C[C@@H](C)C(O)=O)[C@@]3(C)[C@@H](O)C[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12

InChI Key InChIKey=NPBCMXATLRCCLF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300200   

TargetG-protein coupled bile acid receptor 1(Human)
Universita Di Perugia

Curated by ChEMBL
LigandPNGBDBM50300200(6alpha-ethyl-23(R)-methyl-cholic acid | CHEMBL5652...)
Affinity DataEC50:  820nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells assessed as increase in CRE-driven gene expression by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Universita Di Perugia

Curated by ChEMBL
LigandPNGBDBM50300200(6alpha-ethyl-23(R)-methyl-cholic acid | CHEMBL5652...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at FXR expressed in COS1 cells by cell-based bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed