BDBM50300298 4-Amino-N-(3-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide::CHEMBL567225

SMILES Nc1nonc1C(NO)=Nc1cccc(F)c1

InChI Key InChIKey=GDNWRODWALZFSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300298   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50300298(4-Amino-N-(3-fluorophenyl)-N'-hydroxy-1,2,5-oxadia...)
Affinity DataIC50: 270nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase in IFN-gamma-stimulated human HeLa cells assessed as kynurenine formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50300298(4-Amino-N-(3-fluorophenyl)-N'-hydroxy-1,2,5-oxadia...)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal his-tagged human indoleamine 2,3-dioxygenase expressed in Escherichia coli assessed as N'-formylkynurenine formation by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed