BDBM50300499 (S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydroxy-3-[7-(2-methanesulfonyl-ethyl)-1,1-dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl]-1,5-dihydro-pyrrol-2-one::CHEMBL575742

SMILES CC(C)(C)[C@@H]1N(Cc2ccc(F)cc2)C(=O)C(C1=O)=C1NS(=O)(=O)c2c1cccc2CCS(C)(=O)=O

InChI Key InChIKey=LKJGWEMMQICXAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300499   

TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300499((S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydroxy-3-[...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed