BDBM50300503 CHEMBL582995::N-({3-[(5S)-5-tert-butyl-1-[(4-fluoro-3-methylphenyl)methyl]-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-1,1-dioxo-{6},2-benzothiazol-7-yl}methyl)aminosulfonamide

SMILES Cc1cc(CN2[C@H](C(=O)C(C3NS(=O)(=O)c4c3cccc4C=NS(N)(=O)=O)C2=O)C(C)(C)C)ccc1F

InChI Key InChIKey=CFHARFYVWJMNEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300503   

TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300503(N-({3-[(5S)-5-tert-butyl-1-[(4-fluoro-3-methylphen...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed