BDBM50300568 (+/-)-5-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid::CHEMBL573680

SMILES OC(=O)C1CCCc2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cccc12

InChI Key InChIKey=OHQDOFBGVQTUAB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300568   

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50300568((+/-)-5-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human LXRbeta assessed as association of SRC1 to LXRbeta ligand binding domain by FRET based cell-free ligand sensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50300568((+/-)-5-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2...)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human LXRalpha assessed as association of SRC1 to LXRalpha ligand binding domain by FRET based cell-free ligand sensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed