BDBM50300579 (R)-2-(3-{3-[[2-Chloro-3-(trifluoromethyl)benzyl]-(2,2-diphenylethyl)amino]-2-methyl-propoxy}-phenyl)acetic acid::CHEMBL573587

SMILES C[C@@H](COc1cccc(CC(O)=O)c1)CN(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F

InChI Key InChIKey=DMMRWDJRLGTEMM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300579   

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50300579((R)-2-(3-{3-[[2-Chloro-3-(trifluoromethyl)benzyl]-...)
Affinity DataEC50:  86nMAssay Description:Agonist activity at human LXRbeta assessed as association of SRC1 to LXRbeta ligand binding domain by FRET based cell-free ligand sensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50300579((R)-2-(3-{3-[[2-Chloro-3-(trifluoromethyl)benzyl]-...)
Affinity DataEC50:  280nMAssay Description:Agonist activity at human LXRalpha assessed as association of SRC1 to LXRalpha ligand binding domain by FRET based cell-free ligand sensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed